Citrate used in blood products reduces ionized calcium.

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Multiple Choice

Citrate used in blood products reduces ionized calcium.

Explanation:
Citrate acts as an anticoagulant in stored blood by binding calcium, which removes the ionized calcium needed for the coagulation cascade. When transfused, citrate can bind calcium in the recipient, temporarily lowering ionized calcium levels. In healthy individuals, the liver rapidly metabolizes citrate, so calcium levels rebound quickly. In scenarios such as massive transfusion or liver failure, citrate metabolism may be overwhelmed, leading to hypocalcemia and possible symptoms, with calcium supplementation sometimes required. Therefore, citrate used in blood products reduces ionized calcium.

Citrate acts as an anticoagulant in stored blood by binding calcium, which removes the ionized calcium needed for the coagulation cascade. When transfused, citrate can bind calcium in the recipient, temporarily lowering ionized calcium levels. In healthy individuals, the liver rapidly metabolizes citrate, so calcium levels rebound quickly. In scenarios such as massive transfusion or liver failure, citrate metabolism may be overwhelmed, leading to hypocalcemia and possible symptoms, with calcium supplementation sometimes required. Therefore, citrate used in blood products reduces ionized calcium.

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